Beruflicher Werdegang

Medizinstudium, J. W. Goethe Universität Frankfurt am Main

Klinische Tätigkeiten zur Facharztausbildung in Gynäkologie und Urologie in Krefeld, Duisburg, Dresden

Bestehen des amerikanischen medizinischen Staatsexamina

Forschungsassistentin; Division of Urologiy,

University of California in Los Angeles, USA

Chief Scientific Officer  und Studienplanbeauftragte

der MukoCell GmbH

Ausgewählte Publikationen und publizierte Kongressbeiträgen

Ram-Liebig G, Barbagli G, Heidenreich A, Fahlenkamp D, Romano G, Rebmann U, Standhaft D, van Ahlen H, Schakaki S, Balsmeyer U, Spiegeler ME, Knispel H. Results of Use of Tissue-Engineered Autologous Oral Mucosa Graft for Urethral Reconstruction: A Multicenter, Prospective, Observational Trial. eBioMedicine 2017; EBioMedicine. 2017;23:185-192.

Ram-Liebig G, Bednarz J, Stuerzebecher B, Fahlenkamp D, Barbagli G, Romano G, Balsmeyer U, Spiegeler ME, Liebig S, Knispel H. Regulatory challenges for autologous tissue engineered products on their way from bench to bedside in Europe. Advanced Drug Delivery Reviews 2015;82-83C:181-191.

Engelmann K, Teichmann J, Ram-Liebig G, Valtink M. Welche Möglichkeiten bietet das Tissue Engineering für die Kornea? Zeitschrift für praktische Augenheilkunde und augenärztliche Fortbildung 2014;35 (4):15.

Knispel H, Spiegeler ME, Stuerzebecher B, Fahlenkamp D, Balsmeyer U, Romano G, Lazzeri M, Barbagli G, Ram-Liebig G. Urethroplasty with autologous tissue-engineered oral mucosa graft – Efficacy results in two centers: A safety assessment. Urology 2014;84(4):99.

Knispel H, Spiegeler ME, Stuerzebecher B, Fahlenkamp D, Balsmeyer U, Romano G, Lazzeri M, Barbagli G, Ram-Liebig G. Analysis of an autologous tissue-engineered graft for urethral reconstruction: A safety assessment. Urology2014;84(4):98.

Knispel H, Stuerzebecher B, Spiegler ME, Balsmeyer U, Fahlenkamp D, Barbagl G, Lazzeri M, Romano G, Ram-Liebig G. Safety assessment of a tissue-engineered graft for urethral reconstruction. Urologe A Supplements 2014(S1).

Knispel H, Stuerzebecher B, Spiegler ME, Balsmeyer U, Fahlenkamp D, Barbagli G, Lazzeri M, Romano G, Ram-Liebig G. Clinical applications of autologous tissue-engineered oral mucosa graft for urethroplasty – An efficacy assessment. Urologe A Supplements 2014(S1).

Lazzeri M, Barbagli G, Fahlenkamp D, Romano G, Balsmeyer U, Knispel H, Spiegeler ME, Stuerzebecher B, Ram-Liebig G. Preclinical and clinical examination of tissue-engineered graft for urethral reconstruction (MukoCell^®) with regard to its safety. The Journal of Urology Supplements 2014;191(4):e122–e123.

Beier J, Ram-Liebig G, Pandey A, Keller HJ. Reconstruction of extended urethral stricture with tissue engineered autologous buccal mucosal graft (MukoCell^®). European Urology Supplements 2014;13 (1):eV60.

Knispel H, Spiegler ME, Ram-Liebig G. One-stage urethroplasty with autologous tissue-engineered oral mucosa graft (MukoCell^®) in an on-Onlay technique. Urologe A Supplements 2013;52(S1).

Barbagli G, Ram-Liebig G, Fahlenkamp D, Lazzer Mi: New bulbar urethroplasty using tissue-engineered oral mucosal graft: a preliminary clinical report. The Journal of Urology Supplements 2013;189(4) e1.

Fahlenkamp D, Barbagli G, Romano G, Ram-Liebig G. Urethroplasty with a tissue-engineered oral mucosa graft (MukoCell^®) in patients with bulbar urethral stricture. Urologe A Supplements 2012;51(S1)

Engel O, Ram-Liebig G, Reiß P, Schwaiger B, Pfalzgraf D, Dahlem R, Fisch M. Tissue-engineered buccal mucosa urethroplasty: outcome of our first 10 patients. The Journal of Urology Supplements 2012;187(4):e6.

Ram-Liebig G, Fahlenkamp D, Romano G, Balsmeyer U, Funk R, Barbagli G. Presentation of a potential appropriate method for bulbar urethroplasty with tissue-engineered oral mucosa graft (MukoCell^®). European Urology Supplements2012;11(1): eV8,eV8a

Ram-Liebig G, Engel O, Reiß P, Schwaiger B, Pfalzgraf D, Dahlem R, Fisch M. Tissue-engineered buccal mucosa urethroplasty. Outcome of our first ten patients. European Urology Supplements 2012;11 (1): e621,e621a

Engel O, Ram-Liebig G,. Reiß P, Schwaiger B, Pfalzgraf D, Dahlem R, Fisch M. Tissue-engineered buccal mucosa urethroplasty: Outcome of our first six patients. Urology 2011;78(3A):117.

Ram-Liebig G. Induktion der Prävaskularization von Trägermaterialien auf Kollagen-Basis. Biomaterialien Supplements 2007;8 (S1):68-69.

Ram-Liebig G, Balana B, Ravens U, Haase M, Baretton G, Wirth MP. New approaches in the modulation of bladder smooth muscle cells on viable detrusor constructs. World Journal of Urology 2006;24(4):429-37.

Ram-Liebig G, Haase M, Baretton G, Wirth MP. In vitro prevascularization of biological matrices with human bladder microvascular endothelial cells can be stimulated by bone marrow mesenchymal progenitor cells. European UrologySupplements 2006;5 (2):59.

Wuest M, Ram-Liebig G, Graf EM, Werner C, Ravens U. Influence of Mechanical Stretch on Gene Expression and Contraction in Pig Detrusor Tissue. European Urology Supplements 2006;5(2):297.

Ram-Liebig G, Ravens U, Haase M, Wirth MP. Engineering of bladder muscle tissue: new approaches in the modulation of viable constructs. The Journal of Urology Supplements, 2005;173(4), S1.

Ram-Liebig G, Herrmann B, Haase M, Baretton G, Wirth MP. Engineering of bladder muscle tissue: new approaches in the modulation of viable constructs. European urology Supplements 2005;4(3):243.

Ram-Liebig G, Meye A, Hakenberg OW, Haase M, Baretton G, Wirth MP. Induction of proliferation and differentiation of cultured urothelial cells on acellular biomaterials. British Journal of Urology International 2004;94(6):922-7.

Ram-Liebig G, Hakenberg OW, Wirth MP. Tissue engineering of the urinary bladder. Urologe A 2004;43(10):1217-22.

Ram-Liebig G, Meye A, Hasse M, Baretton G, Hakenberg O, Wirth MP. Modulation of urothelial proliferation and differentiation on large surfaces of four different biomaterials. European Urology Supplements 2004;3(2):85.

Ram-Liebig G, Meye A, Wirth MP. Tissue engineering on small intestinal submucosa: characterization and growth induction of bladder fibroblasts, urothelial cells and smooth muscle cells. European Urology Supplements 2003;2(1):122.

Gershman A, Ram-Liebig G, Fuchs G, Raz S. Endoscopic submucosal implantation of permanent suture material for the potential treatment of urinary incontinence. Journal of Endourology Supplements1997;11(S1):57.

Gershman A, Ram-Liebig G, Fuchs G, Raz S. Bladder wall replacement using a biomedical engineered membrane. Journal of Endourology Supplements 1997;11(S1):57.

Buchbeitrag

“Bulbar Urethroplasty Using Oral Mucosal Tissue-Engineered Graft (MukoCell^®)“ in dem Buch “Art of urethral reconstruction”. Elsevier Health Sciences 2013.

Präsentationen

Knispel H, Spiegeler ME, Stuerzebecher B, Fahlenkamp D, Balsmeyer U, Romano G, Lazzeri M, Barbagli G, Ram-Liebig G. Urethroplasty with autologous tissue-engineered oral mucosa graft – Efficacy results in two centers: A Safety Assessment. Société Internationale d’Urologie 2014 Glasgow.

Knispel H, Spiegeler ME, Stuerzebecher B, Fahlenkamp D, Balsmeyer U, Romano G, Lazzeri M, Barbagli G, Ram-Liebig G. Analysis of an autologous tissue-engineered graft for urethral reconstruction: A safety assessment. Société Internationale d’Urologie 2014 Glasgow.

Knispel H, Stuerzebecher B, Spiegler ME, Balsmeyer U, Fahlenkamp D, Barbagl G, Lazzeri M, Romano G, Ram-Liebig G. Safety assessment of a tissue-engineered graft for urethral reconstruction. Deutsche Gesellschaft für Urologie 2014 Düsseldorf.

Knispel H, Stuerzebecher B, Spiegler ME, Balsmeyer U, Fahlenkamp D, Barbagli G, Lazzeri M, Romano G, Ram-Liebig G. Clinical applications of autologous tissue-engineered oral mucosa graft for urethroplasty. An efficacy assessment. Deutsche Gesellschaft für Urologie 2014 Düsseldorf.

Lazzeri M, Barbagli G, Fahlenkamp D, Romano G, Balsmeyer U, Knispel H, Spiegeler ME, Stuerzebecher B, Ram-Liebig G. Preclinical and clinical examination of tissue-engineered graft for urethral reconstruction (MukoCell^®) with regard to its safety. American Urologic Association 2014 Orlando.

Beier J, Ram-Liebig G, Pandey A, Keller HJ. Reconstruction of extended urethral stricture with tissue engineered autologous buccal mucosal graft (Mukocell^®). European Association of Urology 2014 Stockholm.

Ram-Liebig G: Harnröhrenrekonstruktion mit autologem Mundschleimhautkonstrukt MukoCell^®. Intensivkurs für Theorie und Praxis: Rekonstruktive Chirurgie der Urethra 2013 Essen.

Knispel H, Spiegler ME, Ram-Liebig G. One-stage urethroplasty with autologous tissue-engineered oral mucosa graft (MukoCell^®) in an on-Onlay technique. Deutsche Gesellschaft für Urologie 2013 Dresden.

Barbagli G, Ram-Liebig G, Romano G, Fahlenkamp D, Balsmeyer U, Lazzeri M. New bulbar urethroplasty using tissue-engineered oral mucosal graft: a preliminary clinical report. American Urological Association 2013 San Diego.

Reichert M, Aragona MS, Ekrutt J, Bischoff C, Sayedahmed K, Seibel R, Riepenhusen J, Urban K, Jacherzt T, Olianas R, Ram-Liebig G.: Die Urethroplastik mit angezüchetetem Mundschleimhaut Gewebe: Ein vorläufiger Bericht unserer ersten Ergebnisse. 7. Nordkongress Urologie 2013 Hamburg.

Ram-Liebig G. Harnröhrenrekonstruktion mit autologem Zelltransplantat MukoCell^®. 4. Kongress Industrielle Zelltechnik  2013 Lübeck.

1. Ram-Liebig: Tissue engineered oral mucosa. Conference Sava Perovic’s Memorial 2012 Arezzo.

Fahlenkamp D, G. Barbagli, U. Balsmeyer, G. Romano, G. Ram-Liebig: Urethroplasty with a tissue-engineered oral mucosa graft (MukoCell^®) in patients with bulbar urethral stricture. Deutsche Gesellschaft für Urologie 2012 Berlin.

Engel O, Ram-Liebig G, Reiß P, Schwaiger B, Pfalzgraf P, Dahlem R, Fisch M. Tissue-engineered buccal mucosa urethroplasty: outcome of our first 10 patients. American Urologic Association 2012 Atlanta.

Ram-Liebig G, Engel O, Schwaiger B, Reiss P, Pfalzgraf D, Dahlem R, Fisch M. Tissue-engineered buccal mucosa urethroplasty. Outcome of our first 10 patients. European Association of Urology 2012 Paris.

Ram-Liebig G, Fahlenkamp D, Romano G, Balsmeyer U, Funk R, Barbagli G. Presentation of a potential appropriate method for bulbar urethroplasty with tissue-engineered oral mucosa graft (MukoCell^®). European Association of Urology 2012 Paris.

Engel O, Ram-Liebig G, Pfalzgraf D, Reiss P, Fisch M, Dahlem R. Tissue- engineered buccal mucosa urethroplasty: Outcome of our first patients. Société Internationale d’Urologie 2011 Berlin.

Ram-Liebig G. Development and production of functional autologous tissue constructs for the reconstruction of urethra and urinary bladder. Biotech and Finance Forum 2007 Stuttgart.

Ram-Liebig G. Induktion der Prävaskularisation von Trägermaterialien auf Kollagen-basis. Symposium Biomaterialien in der Allgemeinchirurgie 2007 Warnemünde.

Ram-Liebig G. Induction of prevascularisation of biological matrices by human bone marrow mesenchymal progenitor cells. Deutsche Gesellschaft für Urologie 2007 Hamburg.

Ram-Liebig G. Entwicklung der wissenschaftlich-technischen Methodik zur in-vitro-Erzeugung funktionierender autologer Gewebs-Konstrukte zum Einsatz in der rekonstruktiven Chirurgie der unteren Harnwege. BMBF-Biofuture2007 Berlin.

Ram-Liebig G. Tissue engineering unterer Harnorgane mit autologen, gewebespezifischen Zellen. BMBF-Go-Bio 2006 Berlin.

Ram-Liebig G, Haase M, Baretton G, Wirth MP. In vitro prevascularization of biological matrices with human bladder microvascular endothelial cells can be stimulated by bone marrow mesenchymal progenitor cells. European Assocation of Urolgoy 2006 Paris.

Ram-Liebig G, Wirth MP. Modulation von Harnblasenzellen auf biologischen Matrices. 5. Workshop Tissue Engineering in der Urologie 2006 Essen.

Ram-Liebig G, Wirth MP. Tissue-engineerter Detrusor, neue Ansätze. 4. Urological Tissue Engineering Meeting 2005 Tübingen.

Ram-Liebig G, Ravens U, Haase M, Wirth MP. Engineering of bladder muscle tissue: new approaches in the modulation of viable constructs. American Urologic Association 2005 San Antonio.

Ram-Liebig G, Herrmann B, Haase M, Baretton G, Wirth MP. Engineering of bladder muscle tissue: new approaches in the modulation of viable constructs. European Association of Urology 2005 Istanbul.

Ram-Liebig G, Meye A, Hasse M, Baretton G, Hakenberg O, Wirth MP. Modulation of urothelial proliferation and differentiation on large surfaces of four different biomaterials. European Association of Urology 2004 Vienna.

Ram-Liebig G, Meye A, Wirth MP. Tissue engineering on small intestinal submucosa: characterization and growth induction of bladder fibroblasts, urothelial cells and smooth muscle cells. European Association of Urology 2003 Madrid.

Patente

Device for introducing a tisssue substituteinto a hollow organ. Patent Nr: EP000003165196A1

Prevascularized tissue transplant constructs for the reconstruction of a human or animal organ.  Patent Nr: EP1989293-A2

Tissue Graft structure that can be sutured for reconstructing a human or animal organ.  Patent Nr: EP2477666-A1

Graft structure comprising terminally differentiated tissue cells for the reconstruction of an organ. Patent Nr: EP1843803-A2

Method for production of a tissue transplant construct for reconstruction of a human or animal organ. Patent Nr: EP1868659-A1

Graft structure comprising terminally differentiated tissue cells for the reconstruction of an organ. Patent Nr: WO/2006/012837

Prevascularized tissue transplant constructs for the reconstruction of a human or animal organ. Patent Nr: WO/2007/098742

Tissue graft structure that can be sutured for reconstructing a human or animal organ. Patent Nr: WO/2011/091796

Method for production of a tissue transplant construct for reconstruction of a human or animal organ. Patent Nr. WO/2006/108408

Constructions de transplantation tissulaire prevascularisees destinees a la reconstruction d’ un organe humain ou animal. Patent Nr. CA2643711-A1

Prevascularized tissue transplant constructs for the reconstruction of a human or animal organ. Patent Nr: AU2007219520

Gewebetransplantatkonstrukt zur Rekonstruktion eines menschlichen oder tierischen Organs. Patent Nr: DE102004037184-B3

Verfahren zur Herstellung eines Gewebetransplantatkonstruktes zur Rekonstruktion eines menschlichen oder tierischen Organs. Patent Nr: DE102005017000-B4

Process for producing a tissue transplant construct for reconstructing a human or animal organ. Patent Nr: US000007851217-B2

Mitgliedsschaften

European Urologic Association

Deutsche Gesellschaft für Urologie

Ärztekammer Nordrhein

Preise

1. FutureSax Business Plan Wettbewerb, Bio- and Nanotechnology 2007, Leipzig.

2. Forschungspreis in Experimenteller Urologie, 2004, Lübeck.